Last data update: May 06, 2024. (Total: 46732 publications since 2009)
Records 1-4 (of 4 Records) |
Query Trace: Kilburn K[original query] |
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The Health Innovation Impact Checklist: a tool to improve the development and reporting of impact models for global health innovations
Shahid M , Finnegan A , Kilburn K , Udayakumar K , Baumgartner JN . Glob Health Action 2022 15 (1) 2056312 Donor financing is increasingly relying on performance-based measures that demonstrate impact. As new technologies and interventions enter the innovation space to address global health challenges, innovators often need to model their potential impact prior to obtaining solid effectiveness data. Diverse stakeholders rely on impact modeling data to make key funding and scaling decisions. With a lack of standardized methodology to model impact and various stakeholders using different modeling strategies, we propose that a universal innovation impact checklist be used to aid in transparent and aligned modeling efforts. This article describes a new Health Innovation Impact Checklist (HIIC) - a tool developed while evaluating the impact of health innovations funded under the Saving Lives at Birth (SL@B) program. SL@B, a global health Grand Challenge initiative, funded 116 unique maternal and newborn health innovations, four of which were selected for cost-effectiveness analyses (CEAs) within our evaluation. A key data source needed to complete a CEA was the lives saved estimate. HIIC was developed to help validate draft impact models from the SL@B donors and our own team's additional modeling efforts, to ensure the inclusion of standardized elements and to pressure test assumptions for modeling impact. This article describes the core components of HIIC including its strengths and limitations. It also serves as an open call for further reviewing and tailoring of this checklist for applicability across global efforts to model the impact of health innovations. |
STORCH Infections among very low birth weight and preterm infants: 2018-2020
Edwards EM , Greenberg LT , Ehret DEY , Soll RF , Lanzieri TM , Horbar JD . Pediatrics 2022 149 (1) RESEARCH BRIEFS| DECEMBER 29 2021 | STORCH Infections Among Very Low Birth Weight and Preterm Infants: 2018–2020 | Erika M. Edwards, PhD, MPH; Lucy T. Greenberg, MS; Danielle E.Y. Ehret, MD, MPH; Roger F. Soll, MD; Tatiana M. Lanzieri, MD, MPH; Jeffrey D. Horbar, MD | FINANCIAL DISLOSURE: The authors have indicated they have no financial relationships relevant to this article to disclose. | POTENTIAL CONFLICT OF INTEREST: Drs Edwards and Ehret receive salary support from Vermont Oxford Network (VON). Ms Greenberg is a VON employee. Dr Soll is vice president, director of clinical trials and follow-up, and director of Cochrane at VON and an unpaid member of the VON Board of Trustees. Dr Horbar is the president and chief executive and chief scientific officer of VON and an unpaid member of the VON Board of Trustees; and Dr Lanzieri has indicated she has no potential conflicts of interest to disclose. | Address correspondence to Erika M. Edwards, PhD, MPH, Vermont Oxford Network, 33 Kilburn St, Burlington, VT 05401. E-mail: eedwards@vtoxford.org | Pediatrics (2022) 149 (1): e2021053655. | https://doi.org/10.1542/peds.2021-053655 | Article history | Split-Screen | Views Icon | Views | PDF | Share Icon | Share | Tools Icon | Tools | Search Site | Subjects:Infectious Diseases, Neonatology | Syphilis, toxoplasmosis, other infections (varicella zoster virus, parvovirus B19), rubella, cytomegalovirus, and herpes simplex virus (STORCH) infections may result in neonatal disease and neurologic sequalae.1 Population-based prevalence rates of STORCH infections among very low birth weight (VLBW) and/or preterm infants in the United States are lacking. |
Antifungal Resistance Trends of Candida auris Clinical Isolates, New York-New Jersey, 2016-2020
Kilburn S , Innes G , Quinn M , Southwick K , Ostrowsky B , Greenko JA , Lutterloh E , Greeley R , Magleby R , Chaturvedi V , Chaturvedi S . Antimicrob Agents Chemother 2022 66 (3) aac0224221 About 55% of U.S. Candida auris clinical cases were reported from New York and New Jersey from 2016 through 2020. Nearly all New York-New Jersey clinical isolates (99.8%) were fluconazole resistant, and 50% were amphotericin B resistant. Echinocandin resistance increased from 0% to 4% and pan-resistance increased from 0 to <1% for New York C. auris clinical isolates but not for New Jersey, highlighting the regional differences. |
The effects of low to moderate prenatal alcohol exposure in early pregnancy on IQ in 5-year-old children
Falgreen Eriksen HL , Mortensen E , Kilburn T , Underbjerg M , Bertrand J , Stovring H , Wimberley T , Grove J , Kesmodel U . BJOG 2012 119 (10) 1191-200 OBJECTIVE: To examine the effects of low to moderate maternal alcohol consumption during early pregnancy on children's intelligence (IQ) at age 5 years. DESIGN: Prospective follow-up study. SETTING: Neuropsychological testing in four Danish cities 2003-2008. POPULATION: A cohort of 1628 women and their children sampled from the Danish National Birth Cohort. METHODS: Participants were sampled based on maternal alcohol consumption during pregnancy. At 5 years of age, children were tested with the Wechsler Preschool and Primary Scale of Intelligence-Revised (WPPSI-R). Parental education, maternal IQ, maternal smoking in pregnancy, the child's age at testing, gender, and tester were considered core confounding factors, whereas the full model also controlled for maternal binge drinking, age, BMI, parity, home environment, postnatal smoking in the home, health status, and indicators for hearing and vision impairments. MAIN OUTCOME MEASURES: The WPPSI-R. RESULTS: No differences in test performance were observed between children whose mothers reported consuming between one and four or between five and eight drinks per week at some point during pregnancy, compared with children of mothers who abstained. For women who reported consuming nine or more drinks per week no differences were observed for mean differences; however, the risks of low full-scale IQ (OR 4.6; 95% CI 1.2-18.2) and low verbal IQ (OR 5.9; 95% CI 1.4-24.9) scores, but not low performance IQ score, were increased. CONCLUSIONS: Maternal consumption of low to moderate quantities of alcohol during pregnancy was not associated with the mean IQ score of preschool children. Despite these findings, acceptable levels of alcohol use during pregnancy have not yet been established, and conservative advice for women continues to be to avoid alcohol use during pregnancy. |
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